Food and omics: unraveling the role of food in breast cancer development

Breast cancer is the second most common worldwide and cause of death for women. Its plasticity variability suggest a multifactorial origin, with powerful influence environmental factors. Current scientific evidence pinpoints food specific nutrients as crucial factors in breast tumor development. More precisely, dietary components can actively participate suppression and/or progression by introducing modifications into epigenetic landscapes cancer. Food not only target oncogenes tumor-suppressor genes modify their methylation levels, but they also histone chemical modifications, non-coding RNA pathways microbiota metabolism. currently treated surgery, radiotherapy, chemotherapy therapies targeting estrogen receptor (ER) human epidermal growth factor 2 (HER2). However, holistic omics study association between diet health opens an interesting alternative future prevention therapy.